All you need to do on a liter bike to stay rubber side down is to use less throttle. The only real difference between a 20HP bike and a 200 HP bike is the user. You can ride the R1 in the lower RPM and it will not have any/much more power than your 250. Whenever you ride a new bike just make sure you grab the throttle with your wrist lower than you normally would grab the throttle of your 250. The sudden acceleration bigger HP bikes can generate will throw an unsuspecting rider backwards with force and if you grab the throttle with your wrist higher up, you will be unable to roll off to save your life. The throttle tube on the R1 is a bit quicker to max than the one for my Ducati 999 (They use the R1 throttle on the 999 as a cheap "quick turn" throttle) so if you are really worried buy a 999 throttle tube for $12 off Ebay and it will take more rotation to hit full steam. As long as you use little throttle then the bike will not accelerate any faster than you can handle.
The second thing to remember is that the clutch lever will remove all power in any crazy situation. Should you find yourself suddenly accelerating waaayyy too fast, just pull the clutch lever. You must be careful when you do this because if you are mid corner at lean or if the rear is sliding, this will have bad results but most of the panic type acceleration is usually with the bike upright and pointed in a straightish line, and this is the best time to use this technique.
Last, speed on these bikes can sneak up on you. When you are used to a 250 turning 13,000 RPM at 100 MPH and then get on a 1000cc, you may find yourself at 125mph @ 8,000 RPM. Just be very aware of what the speedo says until you get used to the mind warping speed these bikes are capable. I have a 1997 Ducati 916 with maybe 100HP and it hit 110 MPH at 9,500RPM today at half throttle. The bike you are getting will most likely hit 100 in first with the front tire rising quickly. Just take it real easy with the throttle and you will find that the bike is as easy to ride as your 250 just with much more speed and acceleration potential, all of which your wrist and brain control.
All you need to do is ride gentle and carefully until you are comfortable and know your new machine. Congratulations and have fun, dont be scared just careful. Cover the clutch, front brake and rear brake and keep the rpm and speed down until you have many miles on the new ride. Like everything on motorcycles, just make small steps and keep your head on a swivel
